skin injuries across the body continue to disrupt everyday life for millions of patients and result in prolonged hospital stays, infection, and death. advances in wound healing devices have improved clinical practice but have mainly focused on ...
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made of fibrous connective tissue, tendons attach muscles to bones in the body, transferring force when muscles contract. but tendons are especially prone to tearing. achilles tendinitis, one of the most common and painful sports injuries, can take months to heal, and injury often recurs. michigan tech researcher rupak rajachar is developing a minimally-invasive, injectable . . .
heal from your past - welcome to the home of energy healing & the accelerated release technique. art is a truly unique modality of energy healing. your past can’t change, but you can.
vituity's community-based model for wound care improves outcomes, reduces system burden, and keeps patients within your network.
researchers have found a new way of accelerating wound healing. the technology and the mode of action involves using lactic acid bacteria as vectors to produce and deliver a human chemokine on site in the wounds. the research group is the first in the world to have developed the concept for topical use and the technology could turn out to be disruptive to the field of biologic drugs.
injectable microporous scaffolds assembled from annealed microgel building blocks whose properties can be tailored by microfluidic fabrication facilitate rapid wound healing in vivo.
a multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial was conducted to test the efficacy of a specifically programmed, low-intensity, non-thermal, pulsed ultrasound medical device for shortening the time to...
piezoelectric effect produces an electrical signal when stress is applied to the bone. when the integrity of the bone is destroyed, the biopotential within the defect site is reduced and several physiological responses are initiated to facilitate healing. during the healing of the bone defect, the b …
when you’re dealing with chronic health issues, finding relief can be a slow and frustrating process. our advanced approach goes beyond typical prescriptions to also include innovative testing, targeted nutritional therapies, and lifestyle interventions that can help you heal and proactively manage your health.
the food and drug administration (fda) is correcting a notice that appeared in the federal register of november 9, 1994 (59 fr 55847). the document announced the approval of the exogentm, inc., sonic accelerated fracture healing system (safhs). some information was inadvertently omitted and...
satisfactory healing of the osteoporotic fracture is critically important to functional...
diabetic infected wounds are one of the major threats to public health but traditional wound dressings always have poor therapeutic efficacy influenced by the single treatment principle and limited penetration depth. herein, we developed a novel kind of multifunctional degradable and removable zwitterionic m
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discover groundbreaking research on wound repair, keloid, and hypertrophic scar treatments. laser studies show short-term improvement, but our microcurrent and ultra-low energy research demonstrates significant healing with no reoccurrence. age-independent wound healing challenges conventional beliefs.
are you tired of waiting weeks for injuries to heal? cold laser therapy works at the cellular level to speed up your body
delayed fracture healing is a major health issue involved with aging. therefore, strategies to improve the pace of repair and prevent non-union are needed in order to improve patient outcomes and lower healthcare costs. in order to accelerate bone fracture healing noninvasively, we sought to develop a drug delivery system that could safely and effectively be used to deliver therapeutics to the site of a bone fracture. we elected to pursue the promising strategy of using small-molecule drug conjugates that deliver therapeutics to bone in an attempt to increase the efficacy and safety of drugs for treating bone-related diseases.this strategy also opened the door for new methods of administering drugs. traditionally, administering bone anabolic agents to treat bone fractures has relied entirely on local surgical application. however, because it is so invasive, this method’s use and development has been limited. by conjugating bone anabolic agents to bone-homing molecules, bone fracture treatment can be performed through minimally invasive subcutaneous administration. the exposure of raw hydroxyapatite that occurs with a bone fracture allows these high-affinity molecules to chelate the calcium component of hydroxyapatite and localize primarily to the fracture site.many bone-homing molecules (such as bisphosphonates and tetracycline targeting) have been developed to treat osteoporosis. however, many of these molecules have toxicity associated with them. we have found that short oligopeptides of acidic amino acids can localize to bone fractures with high selectivity and with very low toxicity compared to bisphosphonates and tetracyclines.we have also demonstrated that these molecules can be used to target peptides of all chemical classes: hydrophobic, neutral, cationic, anionic, short, and long. this ability is particularly useful because many bone anabolics are peptidic in nature. we have found that acidic oligopeptides have better persistence at the site of the fracture than bisphosphonate-targeted therapeutics. this method allows for a systemic administration of bone anabolics to treat bone fractures, which it achieves by accumulating the bone anabolic at the fracture site. it also opens the door for a new way of treating the prevalent afflictions of broken bones and the deaths associated with them.we further developed this technology by using it to deliver anabolic peptides derived from growth factors, angiogenic agents, neuropeptides, and extracellular matrix fragments. we found several promising therapeutics that accelerated the healing of bone fractures by improving the mineralization of the callus and improving the overall strength. we optimized the performance of these molecules by improving their stability, targeting ligands, linkers, dose, and dosing frequency.we also found that these therapeutics could be used to accelerate bone fracture repair even in the presence of severe comorbidities (such as diabetes and osteoporosis) that typically slow the repair process. we found that, unlike the currently approved therapeutic for fracture healing (bmp2), our therapeutics improved functionality and reduced pain in addition to strengthening the bone. these optimized targeted bone anabolics were not only effective at healing bone fractures but they also demonstrated that they could be used to speed up spinal fusion. additionally, we demonstrated that acidic oligopeptides have potential to be used to treat other bone diseases with damaged bone.with these targeted therapeutics, we no longer have to limit bone fracture healing to casts or invasive surgeries. rather, we can apply these promising therapeutics that can be administered non-invasively to augment existing orthopedic practices. as these therapeutics move into clinical development, we anticipate that they will be able to reduce the immobilization time that is the source of so many of the deadly complications associated with bone fracture healing, particularly in the elderly.
background electrostimulation (es) therapy for wound healing is limited in clinical use due to barriers such as cumbersome equipment and intermittent delivery of therapy. methods we adapted a human skin xenograft model that can be used to directly examine the nanogenerator-driven es (ng-es) effects on human skin in vivo—an essential translational step toward clinical application of the ng-es technique for wound healing. results we show that ng-es leads to rapid wound closure with complete restoration of normal skin architecture within 7 days compared to more than 30 days in the literature. ng-es accelerates the inflammatory phase of wound healing with more rapid resolution of neutrophils and macrophages and enhances wound bed perfusion with more robust neovascularization. conclusion our results support the translational evaluation and optimization of the ng-es technology to deliver convenient, efficient wound healing therapy for use in human wounds. graphic abstract
betulin wound gel accelerated healing of superficial partial thickness burns: results of a randomized, intra‐individually controlled, phase iii trial with 12‐months follow‐up acceleration of wound healing promises advantages for patients and caregivers in reducing the burden of disease, avoiding complications such as wound infections, and improving the long-term outcome. however, medicines that can accelerate wound
when i first started gaming, one of the hot topics of conversation was always clerical healing and how to stop clerics being nothing more than “holy drip bottles”. over the next 30-odd …
guided by experiments contrasting electrically accelerated recovery with natural healing, this study formulates a model to investigate the importance of electroactive differential growth and morphological changes in tissue repair. it underscores the clinical potential of leveraging electroactive differential growth for improved healing outcomes. the study reveals that voltage stimulation significantly enhances the healing and growth of biological tissues, accelerating the regeneration process across various growth modalities and steering towards isotropic growth conditions that do not favor any specific growth pathways. enhancing the electroelastic coupling parameters improves the efficacy of bioelectric devices, initiating contraction and fortification of biological tissues in alignment with the electric field. this process facilitates swift cell migration and proliferation, as well as oriented growth of tissue. in instances of strain stiffening at elevated strains, the extreme critical growth ratio aligns with the predictions of neo-hookean models. conversely, for tissues experiencing strain stiffening under moderate to very low strain conditions, the strain stiffening effect substantially delays the onset of electroelastic growth instability, ultimately producing a smooth, hyperelastic surface devoid of any unstable morphologies. our investigation, grounded in nonlinear electroelastic field and perturbation theories, explores how electric fields influence differential growth and instability in biological tissues. we examine the interactions among dimensionless voltage, internal pressure, electroelastic coupling, radius ratio, and strain stiffening, revealing their effects on promoting growth and delaying instability. this framework offers insights into the mechanisms behind electroactive growth and its instabilities, contributing valuable knowledge to the tissue healing.
abstract the objective of this study was to evaluate the early osseointegration of two different...
excisional debridement removes dead tissue, helping chronic wounds heal faster. learn its benefits for better recovery in oxnard and ventura.
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regenerates damaged tissue, instantly healing you. in the uncategorized spells category. added in world of warcraft: dragonflight. always up to date.
exudate regulation, which helps maintain an optimal moisture content in the wound bed and protects the surrounding skin from maceration, is a prerequisite for wound healing. in this study, inspired by the natural hierarchical structure of sugarcane, in which vascular bundles are responsible for transporting water and parenchyma cells are responsible for storing sucrose, we fabricated a continuously self-draining sugarcane stem-based dressing to remove exudates from overhydrated wounds. sugarcane cellulosic frameworks (scf), obtained via alkali and de-sugaring treatments of natural sugarcane substrates (ss), were coated with gold nanorods (aunrs) to facilitate photothermal responsiveness under near-infrared (nir) irradiation. by mimicking plant transpiration and incorporating a stimulus-responsive feature, natural ss were transformed into exudate-managing dressing materials for accelerated wound healing. as the obtained sugarcane frameworks (au@scf) contained abundant vascular bundles and exhibited photothermal responsiveness, it was able to self-drain exudates continuously with a high evaporation efficiency (95%). in order to endow the dressing with antibacterial properties, ag nanoparticles (agnps) was incorporated with au@scf to form ag@au@scf. the healing process in a wound model was more rapid with ag@au@scf with nir irradiation than with a commercial dressing. moreover, as the parenchyma cells in ag@au@scf formed closed chambers after de-sugaring, ag@au@scf facilitated effective thermal insulation (thermal conductivity of 0.04 w m-1k-1) for protecting the underlying wound, even when the temperature of the top surface was high (53 °c). as this hierarchical structure is naturally existent in other poaceae plants, which are sustainable green resources, our findings may provide a new strategy for the fabrication of versatile and efficient self-draining dressings for exudate management and wound healing.
the goal of this study is to improve the therapeutic management of diabetic foot ulcers (dfu). the main questions to answer are if a program of non-weight bearing exercise helps the dfu heal faster than standard wound care. this randomized clinical trial will determine how blood flow to the ulcer and whole body metabolism may be improved with exercise. participants will be randomized to either exercise + standard wound care or standard wound care alone and undergo testing for leg blood flow, fitness and measures of metabolism through blood draws. the intervention period is 6-weeks. eligible participants must have an existing foot ulcer uncomplicated by infection and be medically cleared to exercise.
accelerated healing – the ability to heal more quickly than normal. accelerated healing is also known as epithelial cell regeneration, healing factor, high speed regeneration, instant regeneration…
most wounds will heal naturally with time, however, there are some things a person can do to speed up the healing process. learn more.
accelerated resolution therapy is a form of psychotherapy with roots in existing evidence-based therapies but shown to achieve benefits much more rapidly